Semax, like ACTH/MSH-like peptides (melanocortins) exert pleiotropic non-hormonal actions among their larger activities. These classes of peptides control many behaviors such as regulating attention, processes of learning, and memory formation as a result of their pronounced effect on CNS functions.

Currently this peptide is successfully used in treatment of patients with pathologies related to brain circulation dysfunction and with different intellectual- amnestic problems of the CNS. Doctors have prescribed it for many conditions like anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal, and even chronic diseases such as ALS, Parkinson’s, and Alzheimer’s.
Some doctors use it as a preventative measure to protect against chronic disease and to acutely help improve memory and learning processes. It also has a marked antithrombotic and fibrinolytic effect and a gastric protective effect.

It has also been suggested in literature that due to its effect on carboxypeptidase it can also increase physical performance and adaptation capacities in exposure to high intensity exercise. Often prescribed for: Anti-Thrombosis, ADHD/learning, gastric protection, physical exertion, pain improvement and metal toxicities.