Circulatory Support Supports Healthy Vein Function Supports Vascular Integrity A Dietary Supplement Vegetarian - Vegan Botanicals/Herbs Family Owned Since 1968 GMP Quality Assured NOW Vein Supreme is a combination of botanical ingredients for the support of healthy vascular function. Vein Supreme features Trunorin, a clinically tested and patented extract of Prickly Ash Bark, whose characteristic constituents have been found to promote normal venous function and integrity. Also included are Butcher's Broom and Horse Chestnut Seed Extract, both of which have long histories of use for the support of healthy veins.