HFE Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60290-60, E-AB-60290-120, E-AB-60290-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HFE

Target Synonym: HFE; HFE1; HH; HLA-H; MVCD7; TFQTL2

Research Areas: Cancer,Metabolism,Signal Transduction,Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q30201

Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human HFE

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 8kDa/18kDa/27-40kDa

Observed MW: 50kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only