Phospho-YAP (Ser127) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16323-50, BZ16323-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P46937

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Background: YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 54 kDa; Observed MW: 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-YAP in COS7 lysates using Phospho-YAP antibody., Immunohistochemistry analysis of paraffin-embedded Human heart using YAP antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-YAP in Hela cells using YAP antibody and beta-tubulin antibody.

Alternative Name: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Immunogen: Synthetic peptide of human YAP1

Conjugate: Unconjugated

Modification: Phosphorylated