Phospho-PDPK1 (Ser241) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16287-50, BZ16287-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O15530

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Background: Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 63 kDa; Observed MW: 63 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-PDPK1 in 293, PC-12 lysates using Phospho-PDPK1 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using PDK1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-PDPK1 in Hela cells using PDK1 antibody.

Alternative Name: PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1

Immunogen: Synthetic peptide of human PDPK1

Conjugate: Unconjugated

Modification: Phosphorylated