Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord. In a human breast cancer cell line, both reparixin reduced the number of breast cancer stem cells compared with no treatment. I n mice with primary human breast cancer xenografts, reparixin alone or in combination with docetaxel reduced tumor growth compared with saline control. The combination had greater efficacy than either reparixin or docetaxel alone.

Product information

CAS Number: 266359-93-7

Molecular Weight: 429.57

Formula: C20H35N3O5S

Synonym:

Repertaxin L-lysine salt

Chemical Name: (2R)-N-methanesulfonyl-2-[4-(2-methylpropyl)phenyl]propanamide; (2S)-2,6-diaminohexanoic acid

Smiles: CC(C)CC1=CC=C(C=C1)[C@@H](C)C(=O)NS(C)(=O)=O.NCCCC[C@H](N)C(O)=O

InChiKey: JEJFWWFZAQBZMJ-GVKMLHTLSA-N

InChi: InChI=1S/C14H21NO3S.C6H14N2O2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18;7-4-2-1-3-5(8)6(9)10/h5-8,10-11H,9H2,1-4H3,(H,15,16);5H,1-4,7-8H2,(H,9,10)/t11-;5-/m10/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.